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Found 3 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50050525'
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50:  240nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50:  240nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Trustees of Tufts College

US Patent
LigandPNGBDBM50050525((R)-1-((S)-2-aminopropanoyl)pyrrolidin-2-ylboronic...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested in vitro for inhibition of Prolyl endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed