Report error Found 5 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase' and Ligand = 'BDBM50431242'
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:Competitive inhibition of human PREP using Suc-GP-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of PREP (unknown origin) using AMC substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of POP (unknown origin)More data for this Ligand-Target Pair
TargetProlyl endopeptidase(Human)
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Tufts University Sackler School of Biomedical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
