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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor 2' and Ligand = 'BDBM50333500'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333500((R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopropanec...)
Affinity DataKi:  3.60nMAssay Description:Displacement of radioligand from human CRTH2 expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333500((R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopropanec...)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at CRTH2 in human eosinophil assessed as effect of cellular shape change by EOS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333500((R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopropanec...)
Affinity DataIC50:  7.5nMAssay Description:Antagonist activity at human CRTH2 expressed in HEK293 cells assessed as inhibition of forskolin-induced increase intracellular [125I]cAMP level by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed