Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50414549'
Affinity DataKi: 1.26nMAssay Description:Antagonist activity at human EP3 receptor expressed in cells assessed as mobilization of intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.31nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human recombinant EP3 receptor expressed in CHOK1 cells assessed as inhibition of sulprostone-induced decrease in cAMP level p...More data for this Ligand-Target Pair
Affinity DataEC50: >2.51E+4nMAssay Description:Agonist activity at human EP3 receptorMore data for this Ligand-Target Pair