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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50232543'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed