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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50499953'
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499953(CHEMBL3739779)
Affinity DataKi:  52nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499953(CHEMBL3739779)
Affinity DataIC50:  3.10nMAssay Description:Antagonist activity at human EP4 receptor in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499953(CHEMBL3739779)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at EP4 receptor in human whole blood assessed as reversal of inhibition of PGE2 mediated LPS-induced TNF alpha production pretrea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed