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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM22966'
TargetProstaglandin G/H synthase 1(Mouse)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  5.67E+4nMAssay Description:Inhibition of COX1 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Human)
Institute For Chemical Biology and Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >6.60E+4nMpH: 8.0 T: 37°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >6.60E+4nMAssay Description:In vitro inhibitory activity against ovine Prostaglandin G/H synthase 1 (44 nM) using [14C]AA (50 uM) was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed