Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM17325'
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity of the compound against farnesyltransferase (FTase)More data for this Ligand-Target Pair
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataIC50:  1.10nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FT)More data for this Ligand-Target Pair
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataEC50:  16nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM17325((2S)-2-[(4-{[butyl(2-cyclohexylethyl)amino]methyl}...)
Affinity DataEC50:  16nMAssay Description:In vitro effective concentration of the compound against farnesyltransferase (FT)More data for this Ligand-Target Pair