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Found 7 Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50397782'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  15nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  110nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  130nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  140nMAssay Description:Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  170nMAssay Description:Inhibition of Akt 1 in human AN3CA cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  840nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Arqule

Curated by ChEMBL
LigandPNGBDBM50397782(CHEMBL2177834)
Affinity DataIC50:  910nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed