Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 2 Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S]' and Ligand = 'BDBM153705'
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund

LigandPNGBDBM153705(Methyl 1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphth...)
Affinity DataIC50:  600nMAssay Description:IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturer’s instructions. The kinases A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S](Human)
Technische Universit??????T Dortmund

LigandPNGBDBM153705(Methyl 1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphth...)
Affinity DataKd:  900nMpH: 7.4Assay Description:Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed