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Found 5 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50071364'
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50:  10nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50:  40nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (K103N)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50:  230nMAssay Description:Compound was tested for inhibitory activity against HIV-1 wild type reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50:  1.50E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (P236L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071364(5-Ethyl-5H-4,5,6-triaza-dibenzo[a,d]cycloheptene |...)
Affinity DataIC50:  2.50E+3nMAssay Description:Compound was tested for inhibitory activity against HIV-1 mutant type reverse transcriptase (L1001)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed