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Found 4 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50479470'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of wild type HIV1 RT polymerase by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of HIV1 isolate R8 reverse transcriptase Y181C mutant after 90 mins by electrochemiluminescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50479470(CHEMBL489586 | MK-4965)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of HIV1 RT polymerase Y181C mutant by SPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed