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Found 8 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50514843'
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  114nMAssay Description:Inhibition of HIV1 RT in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubated for 1 hr b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  120nMAssay Description:Inhibition of HIV1 RT K103N/Y181C mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  130nMAssay Description:Inhibition of HIV1 RT V106A/F227L mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  141nMAssay Description:Inhibition of HIV1 RT Y181C mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  222nMAssay Description:Inhibition of HIV1 RT K103N mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  228nMAssay Description:Inhibition of HIV1 RT L100I mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  374nMAssay Description:Inhibition of HIV1 RT E138K mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50514843(CHEMBL4526732)
Affinity DataIC50:  452nMAssay Description:Inhibition of HIV1 RT Y188L mutant in presence of reconstituted template and viral nucleotides [digoxigenin (DIG)-dUTP, biotin-dUTP and dTTP] incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed