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1
Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM380132'
Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM380132
(6-methoxy-1-methyl-N- [4-(4-oxo-3,4- dihydrophthal...)
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Affinity Data
IC50: <100nM
Assay Description:
The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...
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Ligand Info
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US Patent
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