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Found
1
Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM386022'
Target
Ribosomal protein S6 kinase beta-1 [T412E]
(Homo sapiens (Human))
Merck Patent
US Patent
Ligand
BDBM386022
(4-{4-[2-dimethylamino-1-(4-trifluoromethyl-phenyl)...)
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Affinity Data
IC50: 750nM
Assay Description:
P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
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In Depth
Details
US Patent
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