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Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50180359'
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180359(2-(3-Oxo-1,3-dihydroisobenzofuran-5-ylamino)-6-(3-...)
Affinity DataIC50:  490nMAssay Description:Growth inhibition in human melanoma cells WM266.4 expressing mutant B-RAF with SRBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50180359(2-(3-Oxo-1,3-dihydroisobenzofuran-5-ylamino)-6-(3-...)
Affinity DataIC50:  740nMAssay Description:Inhibitory activity against human B-RAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed