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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50469457'
TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50469457(CHEMBL4286698)
Affinity DataKi:  11nMAssay Description:Binding affinity to recombinant human GST-tagged mTOR catalytic domain (1360 to 2549 residues) expressed in baculovirus after 1 hr by TR-FRET displac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50469457(CHEMBL4286698)
Affinity DataKi:  11nMAssay Description:Inhibition of alexa fluor 647-labeled kinase tracer 314 binding to recombinant human N-terminal GST-fused mTOR (1360 to 2549 residues) expressed in b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50469457(CHEMBL4286698)
Affinity DataKd:  0.270nMAssay Description:Binding affinity to wild-type human partial length mTOR (L1382 to W2549 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50469457(CHEMBL4286698)
Affinity DataKd:  0.270nMAssay Description:Inhibition of human mTOR (1382 to 2549 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed