Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM50131266'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM50131266(CHEMBL3634758 | US9260425, 173)
Affinity DataKi:  0.0600nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM50131266(CHEMBL3634758 | US9260425, 173)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 mins in presence of ATP by caliper microfluidic mobility shift as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genetech

US Patent
LigandPNGBDBM50131266(CHEMBL3634758 | US9260425, 173)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed