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Found 2 Enz. Inhib. hit(s) with Target = 'Serine-protein kinase ATM' and Ligand = 'BDBM50378398'
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378398(CHEMBL4174323)
Affinity DataIC50:  950nMAssay Description:Inhibition of ATM autophosphorylation at Ser1981 in human HT29 cells preincubated for 1 hr followed by X ray irradiation and measured after 1 hr by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine-protein kinase ATM(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378398(CHEMBL4174323)
Affinity DataIC50:  954nMAssay Description:Inhibition of ATM phosphorylation at Ser-1981 residue in human HT-29 cells incubated for 1 hr followed by X-ray irradiation by Hoechst staining based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed