Found 4 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50446145' TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto At Mississauga
Curated by ChEMBL
University Of Toronto At Mississauga
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Competitive binding affinity to STAT3 SH2 domain (unknown origin) assessed as inhibition of interaction with FAMpYLPQTV after 15 to 30 mins by fluore...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Hawaii Cancer Center
Curated by ChEMBL
University of Hawaii Cancer Center
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of STAT3 DNA binding activity in mouse NIH/3T3 nuclear extract preincubated for 30 mins followed by [32P]hSIE addition measured after 30 m...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto At Mississauga
Curated by ChEMBL
University Of Toronto At Mississauga
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 (unknown origin) binding to DNA by EMSA analysisMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Of Toronto At Mississauga
Curated by ChEMBL
University Of Toronto At Mississauga
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
