Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Smoothened homolog' and Ligand = 'BDBM50383031'
TargetSmoothened homolog(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50383031(CHEMBL2031290)
Affinity DataIC50:  5nMAssay Description:Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50383031(CHEMBL2031290)
Affinity DataIC50:  15nMAssay Description:Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed