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Found 3 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 5 subunit alpha' and Ligand = 'BDBM50465062'
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50465062(CHEMBL4279180 | US10550080, Example 2)
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells at -40 mV holding potential measured after 600 secs by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50465062(CHEMBL4279180 | US10550080, Example 2)
Affinity DataIC50:  1.83E+4nMAssay Description:Ion Works Barracuda population patch clamp (PPC). PPC measurements were performed using an IonWorks Barracuda instrument (Molecular Devices Corporati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50465062(CHEMBL4279180 | US10550080, Example 2)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells after 600 secs at -50 mV holding potential by ion works barracuda population patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed