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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 8 subunit alpha' and Ligand = 'BDBM526203'
TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM526203(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)
Affinity DataIC50:  10nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSodium channel protein type 8 subunit alpha(Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM526203(4-((2-(azetidin-1-ylmethyl)benzyl)amino)-2,6-diflu...)
Affinity DataIC50:  11nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent