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Found 4 Enz. Inhib. hit(s) with Target = 'Sodium channel protein type 9 subunit alpha' and Ligand = 'BDBM236497'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM236497(US9388137, 1)
Affinity DataKi:  6.03E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM236497(US9388137, 1)
Affinity DataKi:  6.03E+3nMAssay Description:On the day of experimentation, the 35 mm dish was placed on the stage of an inverted microscope equipped with a perfusion system that continuously pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM236497(US9388137, 1)
Affinity DataIC50:  872nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM236497(US9388137, 1)
Affinity DataIC50:  872nMpH: 7.3Assay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10× HBSS t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent