Found 4 Enz. Inhib. hit(s) with Target = 'Sodium-dependent serotonin transporter' and Ligand = 'BDBM50168071' TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Inhibition of human SERT I179C mutant expressed in HEK293 MSR cells assessed as [3H]-5-HT uptake preincubated for 30 mins followed addition of [3H]-5...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of wild-type human SERT expressed in HEK293 MSR cells assessed as [3H]-5-HT uptake preincubated for 30 mins followed addition of [3H]-5HT ...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Inhibition of human SERT I172M mutant expressed in HEK293 MSR cells assessed as [3H]-5-HT uptake preincubated for 30 mins followed addition of [3H]-5...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Aarhus University
Curated by ChEMBL
Aarhus University
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human SERT W103A mutant expressed in HEK293 MSR cells assessed as [3H]-5-HT uptake preincubated for 30 mins followed addition of [3H]-5...More data for this Ligand-Target Pair
