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Report error Found 2 Enz. Inhib. hit(s) with Target = 'TGF-beta receptor type-1' and Ligand = 'BDBM50293527'
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293527(2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-...)
Affinity DataIC50:  58nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed