Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK' and Ligand = 'BDBM50547848' TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full-length His-tagged human BTK expressed in baculovirus expression system using fluoresceinated peptide as substrate incu...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of BTK in human Ramos B cells assessed as reduction in goat anti human IgM-stimulated calcium flux preincubated for 1 hr followed by goat ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Bristol Myers Squibb Research
Curated by ChEMBL
Bristol Myers Squibb Research
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of BTK in human whole blood assessed as reduction in goat anti human IgM/human IL4-stimulated CD69 cell surface expression on peripheral B...More data for this Ligand-Target Pair
