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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM147758'
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM147758
(US8962608, 28-76)
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Affinity Data
IC50: 0.0400nM
Assay Description:
The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...
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