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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM366984'
Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Genentech
US Patent
Ligand
BDBM366984
(4,4,4-trifluoro-1-[4-[2- [4-[2-(3- pyridyl)piperid...)
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Affinity Data
Ki: 0.260nM
Assay Description:
The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...
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Target Info
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Ligand Info
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Details
US Patent
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