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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM543497'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543497(BDBM543737 | US11279703, TABLE 3.6)
Affinity DataIC50:  4.80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543497(BDBM543737 | US11279703, TABLE 3.6)
Affinity DataIC50:  4.80nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent