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Report error Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM153214'
TargetTyrosine-protein kinase JAK3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153214(US8993756, 13-1)
Affinity DataIC50:  0.0520nMT: 25°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent