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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3 [795-1124]' and Ligand = 'BDBM458952'
Target
Tyrosine-protein kinase JAK3 [795-1124]
(Homo sapiens (Human))
Almirall
US Patent
Ligand
BDBM458952
(US10759793, Example 96)
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Affinity Data
IC50: 2nM
Assay Description:
The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
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Details
US Patent
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