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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM50431378'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431378(CHEMBL2347414)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431378(CHEMBL2347414)
Affinity DataIC50:  427nMAssay Description:Inhibition of SYK in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431378(CHEMBL2347414)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of SYK in human Ramos cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed