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Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosyl-DNA phosphodiesterase 1' and Ligand = 'BDBM50397343'
TargetTyrosyl-DNA phosphodiesterase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50397343(CHEMBL2170135)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human recombinant Tdp1 expressed in Tdp1 knockout chicken DT40 cells using 5'-32P-labeled 5'-GATCTAAAAGACTT-pY-3' as substrate after 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50397343(CHEMBL2170135)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human recombinant Tdp1 assessed as conversion of 14-mer 5'-32P-labeled 3'-phosphotyrosyl DNA substrate N14Y to 14-mer 5'-32P-labeled 3'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed