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Found 13 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50016187
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593067(CHEMBL3408216)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593061(CHEMBL5183704)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593063(CHEMBL5199011)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593082(CHEMBL5182477)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593065(CHEMBL5186605)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593060(CHEMBL5179085)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593058(CHEMBL5170909)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593081(CHEMBL5204489)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593062(CHEMBL5169918)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593080(CHEMBL5175240)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593083(CHEMBL5200874)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In DepthDetails PubMed