Compile Data Set for Download or QSAR
Report error Found 217 of ic50 for UniProtKB: P04757
LigandChemical structure of BindingDB Monomer ID 50459664BDBM50459664(CHEMBL4218406)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459656BDBM50459656(CHEMBL4214931)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587095BDBM50587095(CHEMBL5084339)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -80 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50445331BDBM50445331(CHEMBL3104245)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238610BDBM50238610(CHEMBL4062759)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238584BDBM50238584(CHEMBL4089797)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459659BDBM50459659(CHEMBL4214003)
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459655BDBM50459655(CHEMBL4210514)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459652BDBM50459652(CHEMBL4215824)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459660BDBM50459660(CHEMBL4206670)
Affinity DataIC50: 7.40nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459661BDBM50459661(CHEMBL4215453)
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238581BDBM50238581(CHEMBL4081435)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238579BDBM50238579(CHEMBL4070842)
Affinity DataIC50: 9.80nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459653BDBM50459653(CHEMBL4211045)
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238580BDBM50238580(CHEMBL4099451)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238585BDBM50238585(CHEMBL4071400)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459654BDBM50459654(CHEMBL4206157)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50445331BDBM50445331(CHEMBL3104245)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days by voltage cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238607BDBM50238607(CHEMBL4069809)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238589BDBM50238589(CHEMBL4061135)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50445330BDBM50445330(CHEMBL3104243)
Affinity DataIC50: 28nMAssay Description:Inhibition of rat alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001696BDBM50001696(CHEMBL3238023)
Affinity DataIC50: 28nMAssay Description:Inhibition of rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes by voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238606BDBM50238606(CHEMBL4099865)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current at -70 mV hold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238617BDBM50238617(CHEMBL4091711)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587092BDBM50587092(CHEMBL5087554)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at rat alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238609BDBM50238609(CHEMBL4100403)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current at -80 mV hold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459658BDBM50459658(CHEMBL4208491)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238583BDBM50238583(CHEMBL4084438)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50554887BDBM50554887(CHEMBL4778777)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238611BDBM50238611(CHEMBL4097007)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459657BDBM50459657(CHEMBL4203617)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50516325BDBM50516325(CHEMBL4463089)
Affinity DataIC50: 168nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50554889BDBM50554889(CHEMBL4746075)
Affinity DataIC50: 181nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001695BDBM50001695(CHEMBL3238085)
Affinity DataIC50: 183nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50554884BDBM50554884(CHEMBL4785148)
Affinity DataIC50: 193nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50567433BDBM50567433(CHEMBL4869892)
Affinity DataIC50: 230nMAssay Description:Inhibition of rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001696BDBM50001696(CHEMBL3238023)
Affinity DataIC50: 265nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50516309BDBM50516309(CHEMBL4594009)
Affinity DataIC50: 283nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001698BDBM50001698(CHEMBL3238083)
Affinity DataIC50: 298nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001699BDBM50001699(CHEMBL3238069)
Affinity DataIC50: 307nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50554886BDBM50554886(CHEMBL4782240)
Affinity DataIC50: 309nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001700BDBM50001700(CHEMBL3238070)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459663BDBM50459663(CHEMBL4204149)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001701BDBM50001701(CHEMBL3238086)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50554891BDBM50554891(CHEMBL4753165)
Affinity DataIC50: 325nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50516329BDBM50516329(CHEMBL4467363)
Affinity DataIC50: 341nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50001702BDBM50001702(CHEMBL3238084)
Affinity DataIC50: 345nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of epibatadine-induced effect after 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50238612BDBM50238612(CHEMBL4089727)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current at -80 mV hold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50459662BDBM50459662(CHEMBL4203278)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of acetyl choline-induced membrane currents p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50516307BDBM50516307(CHEMBL4445542)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
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