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Report error Found 3 of ic50 for UniProtKB: P46098
Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50417287(Aloxi | Aurothioglucose | PALONOSETRON | PALONOSET...)
Affinity DataIC50: 0.880nMAssay Description:Antagonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells assessed as inhibition of 5-HT-induced response after 45 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50459885(CHEMBL1382868)
Affinity DataIC50: 430nMAssay Description:Inhibition of human 5-HT3AB receptor expressed in transient A201 cells after 30 mins by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50150673([(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-n...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]GR-65630 binding to rabbit ileum muscularis 5-HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed