Compile Data Set for Download or QSAR
maximum 50k data
Found 224 of ic50 for UniProtKB: Q00961
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50134218(CHEMBL3741652)
Affinity DataIC50:  900nMAssay Description:Negative allosteric modulation of rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as suppression of 100 uM glutamate and 30 u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324399((E)-4-(6-iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324392((E)-4-(6-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324404((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-phenylquinazolin-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324428((E)-3-(6-Iodo-2-(3-nitrostyryl)-4-oxoquinazolin-3(...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324426((E)-4-(6-iodo-2-(4-nitrostyryl)-4-oxoquinazolin-3(...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324405((E)-4-(2-(3-Nitrostyryl)-4-oxobenzo[g]quinazolin-3...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324397((E)-4-(6-Fluoro-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324398((E)-4-(6-Bromo-2-(3-nitrostyryl)-4-oxoquinazolin-3...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509842(CHEMBL4468229)
Affinity DataIC50:  2.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509840(CHEMBL4528294)
Affinity DataIC50:  2.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324445((E)-6-iodo-3-(2-methoxyphenyl)-2-(2-(pyridin-3-yl)...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324409((E)-4-(2-(3-Nitrostyryl)-4-oxo-6-propylquinazolin-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509841(CHEMBL4445076)
Affinity DataIC50:  3.20E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509834(CHEMBL4583491)
Affinity DataIC50:  3.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324411(4-(2-(3-Nitrostyryl)-4-oxo-6-styrylquinazolin-3(4H...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324473((E)-3-(2-methoxyphenyl)-2-(2-nitrostyryl)quinazoli...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324410((E)-4-(2-(3-nitrostyryl)-4-oxo-6-(thiophen-2-yl)qu...)
Affinity DataIC50:  5.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324400((E)-4-(6-Methyl-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50165461((S)-1-(4-Chloro-phenyl)-2-((S)-6,7-dimethoxy-2-met...)
Affinity DataIC50:  5.29E+3nMAssay Description:Mean inhibitory concentration against rat N-methyl-D-aspartate (NMDA) glutamate receptor 1a/2C expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324452((E)-4-(6-Iodo-4-oxo-2-(2-(pyridin-3-yl)vinyl)quina...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324408((E)-4-(6-Isopropyl-2-(3-nitrostyryl)-4-oxoquinazol...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324401((E)-4-(6-Methoxy-2-(3-nitrostyryl)-4-oxoquinazolin...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531765(CHEMBL4534780)
Affinity DataIC50:  6.50E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324453((E)-3-(6-Iodo-4-oxo-2-(2-(pyridin-3-yl)vinyl)quina...)
Affinity DataIC50:  7.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531773(CHEMBL4475740)
Affinity DataIC50:  7.90E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324461((E)-4-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324463((E)-3-(2-(2-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...)
Affinity DataIC50:  8.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531766(CHEMBL4472540)
Affinity DataIC50:  8.20E+3nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509838(CHEMBL4440270)
Affinity DataIC50:  8.60E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324380((E)-4-(2-(3-methoxystyryl)-4-oxoquinazolin-3(4H)-y...)
Affinity DataIC50:  9.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324396((E)-4-(6,8-Dichloro-2-(4-nitrostyryl)-4-oxoquinazo...)
Affinity DataIC50:  9.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324427((E)-3-(6-Iodo-2-(4-nitrostyryl)-4-oxoquinazolin-3(...)
Affinity DataIC50:  9.00E+3nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50007024(CHEMBL3237304)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50180890(CHEMBL3818694)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of recombinant rat GluN1a/GluN2C co-expressed in HEK293 cells assessed as suppression of glutamate-induced current by patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324383((E)-4-(4-oxo-2-(3-(trifluoromethyl)styryl)quinazol...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50509835(CHEMBL4443031)
Affinity DataIC50:  1.20E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324394((E)-4-(8-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324459((E)-4-(2-(3-Nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324429((E)-4-(6-Methoxy-2-(4-nitrostyryl)-4-oxoquinazolin...)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324433((E)-4-(6-Iodo-4-oxo-2-styrylquinazolin-3(4H)-yl)be...)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50531772(CHEMBL4593032)
Affinity DataIC50:  1.38E+4nMAssay Description:Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324436((E)-4-(2-(2-(naphthalen-2-yl)vinyl)-4-oxoquinazoli...)
Affinity DataIC50:  1.40E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324417((E)-4-(6,7-Dimethoxy-2-(3-nitrostyryl)-4-oxoquinaz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324382((E)-4-(4-oxo-2-(4-(trifluoromethyl)styryl)quinazol...)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324455((E)-4-(2-(4-nitrostyryl)-4-oxoquinazolin-3(4H)-yl)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324395((E)-4-(6,8-Dichloro-2-(3-nitrostyryl)-4-oxoquinazo...)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324393((E)-4-(7-Chloro-2-(3-nitrostyryl)-4-oxoquinazolin-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324381((E)-4-(2-(2-methoxystyryl)-4-oxoquinazolin-3(4H)-y...)
Affinity DataIC50:  1.60E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50324386((E)-4-(2-(3-hydroxystyryl)-4-oxoquinazolin-3(4H)-y...)
Affinity DataIC50:  1.70E+4nMAssay Description:Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp el...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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