Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for UniProtKB: Q05586
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM50498430(CHEMBL3594112)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant GluN1/GluN2C receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM436689(N-Cyclopropyl-2-[2-oxo-6-[3-(trifluoromethyl)pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2C expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM409486(N-Cyclopropyl-2-[6-[3-(trifluoromethyl)phenyl]pyrr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2C expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic V.V.I.

Curated by ChEMBL
LigandPNGBDBM50259886(CHEMBL2333943)
Affinity DataIC50:  6.80E+4nMAssay Description:Negative allosteric modulation of GluN1a/GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glyc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed