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Found 4 of ec50 for UniProtKB: Q05586
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50597430(DALZANEMDOR | Dalzanemdor)
Affinity DataEC50:  430nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2D receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50164398(CHEMBL3799213)
Affinity DataEC50:  6.20E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2D NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50205849(CHEMBL3938522 | US10280165, Example 1)
Affinity DataEC50:  9.50E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2D receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time inte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2D(Homo sapiens (Human))
Sage Therapeutics

Curated by ChEMBL
LigandPNGBDBM50599751(CHEMBL5092058)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluN1a/GluN2D (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assayMore data for this Ligand-Target Pair
In DepthDetails PubMed