Compile Data Set for Download or QSAR
maximum 50k data
Found 72 of ki for UniProtKB: P28335
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  5nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM35254(2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3...)
Affinity DataKi:  10nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50130272(2a-[3-(4-Phenyl-piperazin-1-yl)-propyl]-2a,3,4,5-t...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50289291(2-Hydroxy-methylolanzapine | CHEMBL100454 | [10-(4...)
Affinity DataKi:  18nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  20nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283335(1-Phenethyl-4-[2-(3-phenyl-prop-2-ynyloxy)-ethyl]-...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50240701(2-Methyl-10-piperazin-1-yl-4H-3-thia-4,9-diaza-ben...)
Affinity DataKi:  23nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001115(8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283326(1-Benzyl-4-(3,3-diphenyl-allyloxymethyl)-piperidin...)
Affinity DataKi:  29nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283331(1-Benzyl-4-[(E)-3-(4-fluoro-phenyl)-allyloxymethyl...)
Affinity DataKi:  31nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001116(8-[4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperi...)
Affinity DataKi:  32nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50218629(CHEMBL282927)
Affinity DataKi:  32nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50088844(4-{4-[4-(4-Phenyl-piperazin-1-yl)-butyl]-phenyl}-t...)
Affinity DataKi:  37nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001117(8-[(3-Phenyl-propylamino)-methyl]-7,8-dihydro-3H-6...)
Affinity DataKi:  39nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283322(1-Benzyl-4-((E)-3-phenyl-allyloxymethyl)-piperidin...)
Affinity DataKi:  44nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50088839(CHEMBL169702 | N-{4-[4-(4-Phenyl-piperazin-1-yl)-b...)
Affinity DataKi:  48nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50133917(((6S,7R)-6-Methyl-6,7,8,9-tetrahydro-naphtho[1,2-b...)
Affinity DataKi:  70nMAssay Description:Tested in vitro for the inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283320(1-Phenethyl-4-(3-phenyl-prop-2-ynyloxy)-piperidine...)
Affinity DataKi:  72nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283336(4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1...)
Affinity DataKi:  81nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283321(1-[2-(4-Fluoro-phenyl)-ethyl]-4-[2-(3-phenyl-prop-...)
Affinity DataKi:  85nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001109(8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylm...)
Affinity DataKi:  93nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50116963(2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)...)
Affinity DataKi:  98nMAssay Description:Binding affinity towards 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283394((E)-N-(1-Benzyl-piperidin-4-yl)-3-phenyl-acrylamid...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50289292(2-Methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-4H-3-t...)
Affinity DataKi:  112nMAssay Description:In vitro binding affinity of compound against neuronal 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50088846(CHEMBL353678 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-e...)
Affinity DataKi:  130nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001110(8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylm...)
Affinity DataKi:  143nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50290663((7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1...)
Affinity DataKi:  146nMAssay Description:Tested in vitro for the inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50088841(CHEMBL352617 | N-{4-[3-(4-Phenyl-piperazin-1-yl)-p...)
Affinity DataKi:  160nMAssay Description:Inhibition of GC1 extended spectrum class C beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001111(8-(4-Ethoxycarbonyl-piperidin-1-ylmethyl)-7,8-dihy...)
Affinity DataKi:  170nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001120(8-(4-Carbamoyl-4-phenylamino-piperidin-1-ylmethyl)...)
Affinity DataKi:  171nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50002268(1-Benzyl-4-(3-phenyl-propoxymethyl)-piperidine; co...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperaz...)
Affinity DataKi:  220nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283328(1-Phenethyl-4-((E)-3-phenyl-allyloxymethyl)-piperi...)
Affinity DataKi:  250nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283329(1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperid...)
Affinity DataKi:  254nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283404((1-Benzyl-piperidin-4-yl)-phenyl-(3-phenyl-prop-2-...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283393(3-Phenyl-propynoic acid (1-benzyl-piperidin-4-yl)-...)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50001119(8-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-ylm...)
Affinity DataKi:  281nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor expressed in CHO cell membranes using [3H]ketanserin (60 Ci/mmol, 1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283333(4-((E)-3-Phenyl-allyloxymethyl)-1-(3-phenyl-propyl...)
Affinity DataKi:  283nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283324(1-Naphthalen-1-ylmethyl-4-((E)-3-phenyl-allyloxyme...)
Affinity DataKi:  284nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283405((1-Benzyl-piperidin-4-yl)-methyl-(3-phenyl-prop-2-...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283325(1-Benzyl-4-[(E)-3-(4-trifluoromethyl-phenyl)-allyl...)
Affinity DataKi:  324nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283337(1-Benzyl-4-((1E,3E)-4-phenyl-buta-1,3-dienyloxymet...)
Affinity DataKi:  547nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283396((1-Benzyl-piperidin-4-yl)-bis-((E)-3-phenyl-allyl)...)
Affinity DataKi:  550nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283330(1-((E)-But-2-enyl)-4-((E)-3-phenyl-allyloxymethyl)...)
Affinity DataKi:  650nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283400((1-Benzyl-piperidin-4-yl)-methyl-((E)-3-phenyl-all...)
Affinity DataKi:  840nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50283327(1-Cyclopropylmethyl-4-[2-(3-phenyl-prop-2-ynyloxy)...)
Affinity DataKi:  947nMAssay Description:Binding affinity towards 5-HT2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
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