Compile Data Set for Download or QSAR
Report error Found 224 of ec50 for UniProtKB: P11388
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataEC50:  30nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213799BDBM50213799(CHEMBL440642)
Affinity DataEC50:  96nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213803BDBM50213803(CHEMBL428339)
Affinity DataEC50:  98nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213805BDBM50213805(CHEMBL7877)
Affinity DataEC50:  160nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213812BDBM50213812(CHEMBL269139)
Affinity DataEC50:  160nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50214091BDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50213795BDBM50213795(CHEMBL268458)
Affinity DataEC50:  330nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50214091BDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213794BDBM50213794(CHEMBL7690)
Affinity DataEC50:  360nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50286492BDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50:  500nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50471783BDBM50471783(CHEMBL121666)
Affinity DataEC50:  500nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50213996BDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50213996BDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:In vitro inhibitior of human DNA topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 87351BDBM87351(m-AMSA | N-[4-(acridin-9-ylamino)-3-methoxyphenyl]...)
Affinity DataEC50:  720nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50127140BDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataEC50:  810nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50286484BDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50:  900nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50212758BDBM50212758(CHEMBL133780)
Affinity DataEC50:  980nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50471915BDBM50471915(CHEMBL434650)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50471911BDBM50471911(CHEMBL342844)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50213294BDBM50213294(CHEMBL8063)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213813BDBM50213813(CHEMBL7960)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213810BDBM50213810(CHEMBL7534)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50231257BDBM50231257(CHEMBL96510)
Affinity DataEC50:  1.20E+3nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50212721BDBM50212721(CHEMBL129840)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50471781BDBM50471781(CHEMBL121442)
Affinity DataEC50:  1.60E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50212858BDBM50212858(CHEMBL422791)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213815BDBM50213815(CHEMBL267251)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50212726BDBM50212726(CHEMBL337666)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50286494BDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50286501BDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50286485BDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50212604BDBM50212604(CHEMBL422265)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50213811BDBM50213811(CHEMBL7769)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50212796BDBM50212796(CHEMBL334608)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50212458BDBM50212458(CHEMBL132656)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50212464BDBM50212464(CHEMBL449700)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50286486BDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  2.60E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50286474BDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

LigandChemical structure of BindingDB Monomer ID 50286474BDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandChemical structure of BindingDB Monomer ID 50214148BDBM50214148(CHEMBL283395)
Affinity DataEC50:  3.00E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Displayed 1 to 50 (of 224 total ) | Next | Last >>
Jump to: