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Found 5 of ec50 for UniProtKB: P48167
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human glycine alpha1beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current respon...More data for this Ligand-Target Pair
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50229711(CHEMBL4074873)
Affinity DataEC50:  171nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50229711(CHEMBL4074873)
Affinity DataEC50:  171nMAssay Description:Positive allosteric modulation of human glycine alpha1beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current respon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50464255(CHEMBL4083687)
Affinity DataEC50:  300nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycine receptor subunit alpha-1/beta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50464234(CHEMBL4284872)
Affinity DataEC50:  600nMAssay Description:Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed