Found 41 of ec50 for monomerid = 1434 TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 3.60nMAssay Description:Inhibition of HIV1 reverse transcriptase by EIAMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:C8166 cells infected with HIV-1 were used for determining the anti-HIV biological activity at the cellular level. The specific method was described b...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 26nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 7 in the article)More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptase (as per ref 8 in the article)More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Binding affinity towards wild type HIV-1 reverse transcriptase (as per ref 10 in the article)More data for this Ligand-Target Pair
Affinity DataEC50: 70nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 6 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 124nMAssay Description:Inhibition of wild-type HIV1 3B reverse transcriptase infected in human MT4 cells assessed as protection against virus-induced cytotoxicity by MTT as...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 168nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incuba...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 240nMAssay Description:Inhibition of HIV-1 reverse transcriptase E138K mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect mea...More data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Concentration required to inhibit HIV-1 reverse transcriptase activity (wild-type) by 50%More data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptase (as per ref 12 in the article)More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 622nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incuba...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of reverse transcriptase L100I mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 1.70E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by spectrophotometryMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 3.15E+3nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 3.92E+3nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incuba...More data for this Ligand-Target Pair
Affinity DataEC50: 4.11E+3nMAssay Description:Inhibition of HIV-1 p66/p51 reverse transcriptase L100I mutant incubated for 40 mins by picogreen dye-based spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 4.69E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 6.50E+3nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+3nMAssay Description:Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+3nMAssay Description:Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.03E+3nMAssay Description:Inhibition of HIV-1 p66/p51 reverse transcriptase K103N mutant incubated for 40 mins by picogreen dye-based spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 8.04E+3nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic ...More data for this Ligand-Target Pair
Affinity DataEC50: 8.08E+3nMAssay Description:Inhibition of HIV-1 p66/p51 reverse transcriptase Y181C mutant incubated for 40 mins by picogreen dye-based spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 9.07E+3nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV-1 infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect incuba...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 9.59E+3nMAssay Description:Inhibition of reverse transcriptase K103N mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of HIV RT K103N/Y181C mutant by cell based assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase Y188L mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of HIV1 RES056 reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells assessed as protection against virus-induced cy...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase K103N/Y181C double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase F227L/V106A double mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytoto...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of reverse transcriptase Y181C mutant in HIV1 infected in human MT4 cells assessed as protection against virus induced cytotoxicity after ...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: >1.50E+4nMAssay Description:Inhibition of HIV1 RES056 reverse transcriptase K103N/Y181C double mutant infected in human MT4 cells assessed as protection against virus-induced cy...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
National Institute Of Pharmaceutical Education And Research
Curated by ChEMBL
Affinity DataEC50: 2.44E+6nMAssay Description:Inhibition of reverse transcriptase E138K mutant in HIV-1 3B infected in human MT4 cells assessed as reduction in virus-induced cytopathic effect inc...More data for this Ligand-Target Pair
