Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ec50 for monomerid = 21414
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21414(4-Alkyl-4-methoxypiperidine derivative, 8f | 4-{4-...)
Affinity DataKi: <1nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21414(4-Alkyl-4-methoxypiperidine derivative, 8f | 4-{4-...)
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50:  62nM EC50:  230nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21414(4-Alkyl-4-methoxypiperidine derivative, 8f | 4-{4-...)
Affinity DataEC50:  230nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed