Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ec50 for monomerid = 50012907
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Madrigal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012907(CHEMBL3261336 | USRE46024, 13)
Affinity DataEC50:  90nMAssay Description:Agonist activity at recombinant His6-tagged THR-beta (unknown origin) expressed in Escherichia coli BL21(DE3) co-expressing RXR preincubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha [225-462]/Thyroid hormone receptor beta [148-410](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50012907(CHEMBL3261336 | USRE46024, 13)
Affinity DataEC50:  92nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Madrigal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012907(CHEMBL3261336 | USRE46024, 13)
Affinity DataEC50:  820nMAssay Description:Agonist activity at recombinant His6-tagged THR-alpha (unknown origin) expressed in Escherichia coli BL21(DE3) co-expressing RXR preincubated for 30 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed