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Found 4 of ec50 for monomerid = 50189288
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  201nMAssay Description:Human embryonic kidney 293 (HEK 293) cells were stably transfected with human TLR7 and an NF-kB-driven luciferase reporter vector (pNifty-Luciferase)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetToll-like receptor 7(Mus musculus)
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  570nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Homo sapiens (Human))
Genomics Institute Of Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed