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Found 2 of ic50 for monomerid = 14190
TargetAurora kinase A(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14190(7-cyclohexyl-N-[4-(morpholin-4-yl)phenyl]-7H-pyrro...)
Affinity DataIC50:  49nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 10 of histone-H3 by purified recombinant murine Aurora-A enzyme....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14190(7-cyclohexyl-N-[4-(morpholin-4-yl)phenyl]-7H-pyrro...)
Affinity DataIC50:  600nMAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 795 of Rb by purified recombinant CDK4. The phosphorylation of s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed