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Found 3 of ic50 for monomerid = 14392
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM14392(3-ethyl-5-{5-[(4-ethylpiperazine-1-)sulfonyl]-2-(2...)
Affinity DataIC50:  1.30nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM14392(3-ethyl-5-{5-[(4-ethylpiperazine-1-)sulfonyl]-2-(2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human corpus cavernosum PDE5 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14392(3-ethyl-5-{5-[(4-ethylpiperazine-1-)sulfonyl]-2-(2...)
Affinity DataIC50:  386nMpH: 7.4 T: 2°CAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed