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Found 3 of ic50 for monomerid = 153384
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Campania "Luigi Vanvitelli

Curated by ChEMBL
LigandPNGBDBM153384(4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-...)
Affinity DataIC50:  65nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM153384(4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidad De Santiago

LigandPNGBDBM153384(4-(4-fluorophenyl)-7-[[[5-[(2S)-1,1,1-trifluoro-2-...)
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed